What causes freckles on the human body?

What causes freckles on the human body?

Freckles are formed when groups of melanocyte cells beneath the skin are triggered by sunlight to increase melanin production.


Asked by: Sophie Webber, by email

Freckles are formed when groups of melanocyte cells beneath the skin are triggered by sunlight to increase melanin production. A regulating protein on the cells (called MCR1) is responsible for controlling this process. People who get lots of freckles have a variant of the protein that encourages greater production. The protein is coded by a dominant gene, which means that people who have freckles are highly likely to produce children who also get freckles.

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